Details

Autor(en) / Beteiligte

• Mai, Yu-Jie
• Li, Rui
• Zou, De-Hui
• Wang, Ya-Fei
• Zhao, Yao-Zhong
• Yang, Ren-Chi
• Wang, Jian-Xiang
• Xiao, Zhi-Jian
• Han, Ming-Zhe
• Qian, Lin-Sheng
• Qiu, Lu-Gui

Titel

The outcome analysis of different treatment regimens in 206 patients with multiple myeloma

Ist Teil von

• Zhōnghuá xuèyèxué zázhì, 2005-04, Vol.26 (4), p.193-196

Ort / Verlag

China

Erscheinungsjahr

2005

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• To analyse the outcome of different regimens for the treatment of patients with multiple myeloma (MM). Response rate, median survival time and overall survival rate of 206 MM patients treated with different protocols were retrospectively analysed. The median survival time, 3- and 5-year overall survival (OS) of 200 MM patients treated with conventional therapy were 30.5 months, 32.0% and 15.8%, respectively. The total response rate and complete response (CR) rate of 195 patients treated with MP regimen and combination chemotherapy (CCT) were 45.6% and 14.9%, respectively. The response rates were higher for the patients treated with CCT than for those treated with MP (50.3% versus 30.4%, P < 0.05). The median survival time, 3- and 5- year OS in MP versus CCT group were 30.0 versus 30.5 months, 22.0% versus 35.0%, 13.2% versus 16.7%, respectively, but all of them have no statistical difference. Compared with those without IFN alpha maintenance therapy, patients received IFN alpha therapy showed a higher respons