Details

Autor(en) / Beteiligte

• Babulas, Vicki
• Factor-Litvak, Pam
• Goetz, Raymond
• Schaefer, Catherine A.
• Brown, Alan S.

Titel

Prenatal Exposure to Maternal Genital and Reproductive Infections and Adult Schizophrenia

Ist Teil von

• The American journal of psychiatry, 2006-05, Vol.163 (5), p.927-929

Ort / Verlag

Washington, DC: American Psychiatric Association

Erscheinungsjahr

2006

Quelle

MEDLINE

Beschreibungen/Notizen

• Objective: In this birth cohort study, the authors examined the relation between prenatal exposure to maternal genital reproductive (G R) infections and schizophrenia in offspring. Method: The birth cohort consisted of 7,794 offspring of pregnancies with prospectively acquired data on maternal G R infections from obstetric records. The authors diagnosed 71 cases of schizophrenia and other schizophrenia spectrum disorders in this cohort. The relationship between maternal G R infections and schizophrenia risk was modeled. Results: Exposure to G R infections during the periconceptional period was associated with a significantly increased risk of schizophrenia and other schizophrenia spectrum disorders, with adjustment for maternal race, education, age, and mental illness. Conclusions: Maternal G R infection during periconception appears to increase the risk of schizophrenia in offspring.