Details

Autor(en) / Beteiligte

• Wu, Xiaofeng
• Li, Xiaoguang
• King, Frank
• Xiao, Jianliang

Titel

Insight into and Practical Application of pH-Controlled Asymmetric Transfer Hydrogenation of Aromatic Ketones in Water

Ist Teil von

• Angewandte Chemie (International ed.), 2005-05, Vol.44 (22), p.3407-3411

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2005

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Much faster, more enantioselective, and more‐productive catalysis was attained in the asymmetric transfer hydrogenation of aromatic ketones with the Noyori–Ikariya Ru–Ts‐dpen catalyst in water under slightly basic conditions (see scheme). At low pH values, the reaction was much less efficient and appears to operate through a different mechanism.