Statistics in medicine, 2005-05, Vol.24 (10), p.1455-1481
2005
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Details
- Autor(en) / Beteiligte
- Titel
- An experimental design for the development of adaptive treatment strategies
- Ist Teil von
- Statistics in medicine, 2005-05, Vol.24 (10), p.1455-1481
- Ort / Verlag
- Chichester, UK: John Wiley & Sons, Ltd
- Erscheinungsjahr
- 2005
- Quelle
- Wiley-Blackwell Full Collection
- Beschreibungen/Notizen
- In adaptive treatment strategies, the treatment level and type is repeatedly adjusted according to ongoing individual response. Since past treatment may have delayed effects, the development of these treatment strategies is challenging. This paper advocates the use of sequential multiple assignment randomized trials in the development of adaptive treatment strategies. Both a simple ad hoc method for ascertaining sample sizes and simple analysis methods are provided. Copyright © 2004 John Wiley & Sons, Ltd.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0277-6715eISSN: 1097-0258DOI: 10.1002/sim.2022Titel-ID: cdi_proquest_miscellaneous_67825892
- Format
- –
- Schlagworte
- Algorithms, Clinical Protocols, Clinical trials, dynamic treatment regimes, Humans, Medical treatment, Models, Statistical, multi-stage decision problems, Problem Solving, Randomized Controlled Trials as Topic, Research Design - statistics & numerical data, Sample Size, sequential multiple assignment randomized trial, Statistical analysis, therapeutic strategies, Therapeutics, treatment algorithms