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An Epidemic of Coccidioidomycosis in Arizona Associated with Climatic Changes, 1998–2001
Ist Teil von
The Journal of infectious diseases, 2005-06, Vol.191 (11), p.1981-1987
Ort / Verlag
United States: The University of Chicago Press
Erscheinungsjahr
2005
Quelle
Oxford Journals 2020 Medicine
Beschreibungen/Notizen
Background Reports of coccidioidomycosis cases in Arizona have increased substantially. We investigated factors associated with the increase Methods We analyzed the National Electronic Telecommunications System for Surveillance (NETSS) data from 1998 to 2001 and used Geographic Information Systems (GIS) to map high-incidence areas in Maricopa County. Poisson regression analysis was performed to assess the effect of climatic and environmental factors on the number of monthly cases; a model was developed and tested to predict outbreaks Results The overall incidence in 2001 was 43 cases/100,000 population, a significant (P<.01, test for trend) increase from 1998 (33 cases/100,000 population); the highest age-specific rate was in persons ⩾65 years old (79 cases/100,000 population in 2001). Analysis of NETSS data by season indicated high-incidence periods during the winter (November–February). GIS analysis showed that the highest-incidence areas were in the periphery of Phoenix. Multivariable Poisson regression modeling revealed that a combination of certain climatic and environmental factors were highly correlated with seasonal outbreaks (R2=0.75) Conclusions Coccidioidomycosis in Arizona has increased. Its incidence is driven by seasonal outbreaks associated with environmental and climatic changes. Our study may allow public-health officials to predict seasonal outbreaks in Arizona and to alert the public and physicians early, so that appropriate preventive measures can be implemented