Chung-hua wai kʿo tsa chih, 2005-03, Vol.43 (5), p.294-297
2005
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- Autor(en) / Beteiligte
- Titel
- The effect of breast cancer specific gene 1 in the prognosis of breast cancer
- Ist Teil von
- Chung-hua wai kʿo tsa chih, 2005-03, Vol.43 (5), p.294-297
- Ort / Verlag
- China
- Erscheinungsjahr
- 2005
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To detect breast cancer specific gene 1 (BCSG1) expression in different breast tissue, analysis its correlation with clinical parameters and evaluate the prognosis of breast cancer. The expression of BCSG1 was detected by reverse transcription-polymerase chain reaction (RT-PCR) in surgical specimens from 84 cases of breast disease patients selected randomly at XinHua Hospital affiliated with Shanghai Second Medical University from September 1999 to December 2002. Of 84 cases, 72 case were breast cancer. Statistic analysis BCSG1 gene expression correlation with clinical parameters of breast cancer. 72 breast cancers were followed up (4 - 43 months) to set up independent prognosis factor by survival analysis. BCSG1 was undetectable in all benign breast lesions, while was detectable in 36.1% of all breast cancer samples (26/72), in which 79.2% of stage III/IV cases were positive (19/24). The expression of BCSG1 was tightly correlated with the stage (P = 0.000) and the size of tumor (P = 0.007). Both ER (P = 0.02
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 0529-5815Titel-ID: cdi_proquest_miscellaneous_67764023
- Format
- –
- Schlagworte
- Adult, Aged, Aged, 80 and over, Breast Neoplasms - diagnosis, Breast Neoplasms - genetics, Breast Neoplasms - pathology, Female, gamma-Synuclein - genetics, Gene Expression, Humans, Middle Aged, Neoplasm Proteins - genetics, Neoplasm Staging, Prognosis, Reverse Transcriptase Polymerase Chain Reaction, RNA, Messenger - genetics