Details

Autor(en) / Beteiligte

• McGuire, Lynanne
• Heffner, Kathi
• Glaser, Ronald
• Needleman, Bradley
• Malarkey, William
• Dickinson, Stephanie
• Lemeshow, Stanley
• Cook, Charles
• Muscarella, Peter
• Melvin, William Scott
• Ellison, Edwin Christopher
• Kiecolt-Glaser, Janice K

Titel

Pain and wound healing in surgical patients

Ist Teil von

• Annals of behavioral medicine, 2006-04, Vol.31 (2), p.165-172

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2006

Quelle

2022 ECC(Springer)

Beschreibungen/Notizen

• Human and animal laboratory studies have shown that stress delays healing of standardized punch biopsy wounds. This 5-week prospective study of 17 women who underwent elective gastric bypass surgery addressed the association between postsurgical pain intensity and subsequent healing of a standard 2.0-mm punch biopsy wound. Participants were assessed 1 week before surgery, within 3 hr before surgery, 1 to 3 days postsurgery, and at weekly intervals for 4 weeks following surgery. Patient ratings of greater acute postsurgical pain, averaged over Days 1 and 2 postsurgery, and greater persistent postsurgical pain, averaged over 4 weekly postsurgery pain ratings, were significantly associated with subsequent delayed healing of the punch biopsy wound. Presence of depressive symptoms on the day of surgery, pre-existing persistent pain, and medical complications following initial discharge from the hospital were not related to wound healing. Depressive symptoms on the day of surgery and pre-existing persistent pain did predict persistent postsurgical pain intensity. These findings extend the previous laboratory models of wound healing to a surgical population, providing the first evidence that pain plays an important role in postsurgery wound healing, a key variable in postsurgical recovery.