Details

Autor(en) / Beteiligte

• Fridkin, Scott K
• Hageman, Jeffrey C
• Morrison, Melissa
• Sanza, Laurie Thomson
• Como-Sabetti, Kathryn
• Jernigan, John A
• Harriman, Kathleen
• Harrison, Lee H
• Lynfield, Ruth
• Farley, Monica M

Titel

Methicillin-Resistant Staphylococcus aureus Disease in Three Communities

Ist Teil von

• The New England journal of medicine, 2005-04, Vol.352 (14), p.1436-1444

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• Data on community-acquired methicillin-resistant Staphylococcus aureus infections were obtained by population-based surveillance in Baltimore and Atlanta and by laboratory-based surveillance in Minnesota. From 2001 through 2002, between 8 and 20 percent of all staphylococcal infections were with methicillin-resistant organisms. Most infections involved the skin. A quarter of the patients were hospitalized because of their infections. From 2001 through 2002, between 8 and 20 percent of all staphylococcal infections were with methicillin-resistant organisms. Methicillin-resistant S. aureus infections have become an important clinical problem in the community in patients with no identified risk factors. In the United States, Staphylococcus aureus is the most common cause of skin and soft-tissue infections, as well as of invasive infections acquired in hospitals. 1 , 2 Treatment of serious S. aureus infections can be challenging, and the associated mortality rate remains 20 to 25 percent despite the availability of highly active antimicrobial agents. 3 , 4 However, most antistaphylococcal agents are ineffective against methicillin-resistant S. aureus (MRSA), which was first identified as a hospital-acquired pathogen in the 1960s. 2 , 3 , 5 , 6 Over the past 40 years, MRSA infections have become endemic in most U.S. hospitals 1 , 2 and hospitals worldwide, 7 striking, with rare . . .