Zhong hua yi xue za zhi, 2009-04, Vol.89 (13), p.867-871
2009
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- Autor(en) / Beteiligte
- Titel
- Adipokines and highly active antiretroviral therapy related lipodystrophy: clinical study of 52 cases
- Ist Teil von
- Zhong hua yi xue za zhi, 2009-04, Vol.89 (13), p.867-871
- Ort / Verlag
- China
- Erscheinungsjahr
- 2009
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- To investigate the prevalence of glucose and lipid abnormalities in AIDS patients treated with highly active antiretroviral therapy (HAART) and difference thereof between the HIV-lipodystrophy (LD) and non-HIV-LD groups, and to compare the plasma levels of adiponectin (APN) and leptin (LEP) and their relationship to metabolic disturbance and fat redistribution in these 2 groups. Fifty-two HIV-infected patients were divided into HIV-LD group and non-HIV-LD group according to the patients' reports and doctors' evaluation. Body composition was assessed by whole body dual-energy X-ray absorptiometry. Plasma samples were analyzed for cholesterol, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), insulin, APN, and LEP. The prevalence of dyslipidemia and hyperinsulinemia, the difference of adipocytokine levels, and the relationship of adiponectin, leptin with lipids, insulin as well as fat mass in different body regions were analyzed between the groups. The
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 0376-2491DOI: 10.3760/cma.j.issn.0376-2491.2009.13.002Titel-ID: cdi_proquest_miscellaneous_67578810
- Format
- –
- Schlagworte
- Acquired Immunodeficiency Syndrome - complications, Acquired Immunodeficiency Syndrome - drug therapy, Adiponectin - blood, Adult, Aged, Antiretroviral Therapy, Highly Active, Female, Humans, Hypertriglyceridemia, Insulin - blood, Insulin Resistance, Leptin - blood, Lipids - blood, Lipodystrophy - drug therapy, Lipodystrophy - etiology, Male, Middle Aged