Endocrine reviews, 2005-04, Vol.26 (2), p.203-250
2005
Details
- Autor(en) / Beteiligte
- Titel
- Molecular Endocrinology and Physiology of the Aging Central Nervous System
- Ist Teil von
- Endocrine reviews, 2005-04, Vol.26 (2), p.203-250
- Ort / Verlag
- Bethesda, MD: Endocrine Society
- Erscheinungsjahr
- 2005
- Link zum Volltext
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Aging is associated with a progressive decline in physical and cognitive functions. The impact of age-dependent endocrine changes regulated by the central nervous system on the dynamics of neuronal behavior, neurodegeneration, cognition, biological rhythms, sexual behavior, and metabolism are reviewed. We also briefly review how functional deficits associated with increases in glucocorticoids and cytokines and declining production of sex steroids, GH, and IGF are likely exacerbated by age-dependent molecular misreading and alterations in components of signal transduction pathways and transcription factors.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0163-769XeISSN: 1945-7189DOI: 10.1210/er.2002-0017Titel-ID: cdi_proquest_miscellaneous_67561755
- Format
- –
- Schlagworte
- Aged, Aging - metabolism, Aging - physiology, Animals, Biological and medical sciences, Central Nervous System - metabolism, Central Nervous System - physiology, Circadian Rhythm - physiology, Cognition - physiology, Cytokines - physiology, Development. Senescence. Regeneration. Transplantation, Endocrine System - metabolism, Endocrine System - physiology, Fundamental and applied biological sciences. Psychology, Humans, Hypothalamo-Hypophyseal System - metabolism, Hypothalamo-Hypophyseal System - physiology, Physical Fitness - physiology, Pituitary-Adrenal System - metabolism, Pituitary-Adrenal System - physiology, Vertebrates: nervous system and sense organs