Clinical infectious diseases, 2005-04, Vol.40 (8), p.1173-1180
2005
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Nitazoxanide: A New Thiazolide Antiparasitic Agent
- Ist Teil von
- Clinical infectious diseases, 2005-04, Vol.40 (8), p.1173-1180
- Ort / Verlag
- Chicago, IL: The University of Chicago Press
- Erscheinungsjahr
- 2005
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Nitazoxanide is a new thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of protozoa and helminths. It is given by the oral route with good bioavailability and is well tolerated, with primarily mild gastrointestinal side effects. At present, there are no documented drug-drug interactions. Nitazoxanide has been licensed for the treatment of Giardia intestinalis–induced diarrhea in patients ⩾1 year of age and Cryptosporidum-induced diarrhea in children aged 1–11 years. At present, it is pending licensure for treatment of infection due to Cryptosporidium species in adults and for use in treating immunocompromised hosts. It represents an important addition to the antiparasitic arsenal.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1058-4838eISSN: 1537-6591DOI: 10.1086/428839Titel-ID: cdi_proquest_miscellaneous_67553670
- Format
- –
- Schlagworte
- Antibiotics. Antiinfectious agents. Antiparasitic agents, Antiparasitic agents, Antiparasitic Agents - pharmacology, Biological and medical sciences, Children, Clinical trials, Cryptosporidiosis, Cryptosporidium, Diarrhea, Dosage, Giardia, Human protozoal diseases, Humans, Infections, Infectious diseases, Medical sciences, Medical treatment, Molecular Structure, Parasites, Parasitic diseases, Parasitic Diseases - drug therapy, Parasitism, Parasitology, Pharmacology. Drug treatments, Placebos, Protozoal diseases, Protozoan enzymes, Reviews of Anti-Infective Agents, Side effects, Thiazoles - chemistry, Thiazoles - pharmacology