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ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Ist Teil von
Journal of immunological methods, 2009-08, Vol.347 (1), p.70-78
Ort / Verlag
Amsterdam: Elsevier B.V
Erscheinungsjahr
2009
Quelle
Access via ScienceDirect (Elsevier)
Beschreibungen/Notizen
ELDA is a software application for limiting dilution analysis (LDA), with particular attention to the needs of stem cell assays. It is the first limiting dilution analysis software to provide meaningful confidence intervals for all LDA data sets, including those with 0% or 100% responses. Other features include a test of the adequacy of the single-hit hypothesis, tests for frequency differences between multiple data sets, and the ability to take advantage of cases where the number of cells in the sample is counted exactly. A webtool at
http://bioinf.wehi.edu.au/software/elda/ provides an easy user interface.