Details

Autor(en) / Beteiligte

• Korematsu, Arata
• Furuzono, Tsutomu
• Yasuda, Shoji
• Tanaka, Junzo
• Kishida, Akio

Titel

Nano-scaled hydroxyapatite/polymer composite III. Coating of sintered hydroxyapatite particles on poly(4-methacryloyloxyethyl trimellitate anhydride)-grafted silk fibroin fibers

Ist Teil von

• Journal of materials science. Materials in medicine, 2005-01, Vol.16 (1), p.67-71

Ort / Verlag

United States: Springer Nature B.V

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• A novel composite coupling between nano-scaled hydroxyapatite (HAp) particles and poly[4-methacryloyloxyethyl trimellitate anhydride (4-META)]-grafted silk fibroin (SF) through ionic interaction was synthesized. The weight gain of poly(4-META) by graft-polymerization increased with increasing the reaction time, eventually reaching a plateau value of about 20 wt%. The HAp nano-particles were adsorbed equally and dispersively on the treated SF fiber surface. The HAp content in the composite was 4.554 wt% +/- 0.098 (n = 4), confirmed by thermogravimetry (TG). This synthetic system requires no heat to connect HAp to SF and is useful when applying to non-heat-resistant polymers. The L-929 cell-adhesion test shows that the HAp/SF composite improves bioactivity compared to the original SF.