Details

Autor(en) / Beteiligte

• Ratamess, Nicholas A.
• Kraemer, William J.
• Volek, Jeff S.
• Maresh, Carl M.
• VanHeest, Jaci L.
• Sharman, Matthew J.
• Rubin, Martyn R.
• French, Duncan N.
• Vescovi, Jason D.
• Silvestre, Ricardo
• Hatfield, Disa L.
• Fleck, Steven J.
• Deschenes, Michael R.

Titel

Androgen receptor content following heavy resistance exercise in men

Ist Teil von

• The Journal of steroid biochemistry and molecular biology, 2005, Vol.93 (1), p.35-42

Ort / Verlag

Oxford: Elsevier Ltd

Erscheinungsjahr

2005

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The purpose of the present investigation was to examine androgen receptor (AR) content in the vastus lateralis following two resistance exercise protocols of different volume. Nine resistance-trained men (age = 24.3 ± 4.4 years) performed the squat exercise for 1 (SS) and 6 sets (MS) of 10 repetitions in a random, counter-balanced order. Muscle biopsies were performed at baseline, and 1 h following each protocol. Blood was collected prior to, immediately following (IP), and every 15 min after each protocol for 1 h. No acute elevations in serum total testosterone were observed following SS, whereas significant 16–23% elevations were observed at IP, 15, and 30 min post-exercise following MS. No acute elevations in plasma cortisol were observed following SS, whereas significant 31–49% elevations were observed for MS at IP, 15, and 30 min post-exercise. Androgen receptor content did not change 1 h following SS but significantly decreased by 46% following MS. These results demonstrated that a higher volume of resistance exercise resulted in down-regulation of AR content 1 h post-exercise. This may have been due to greater protein catabolism associated with the higher level of stress following higher-volume resistance exercise.