The Journal of infectious diseases, 2005-03, Vol.191 (6), p.985-989
2005
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Long-Term Shedding of Infectious Epstein-Barr Virus after Infectious Mononucleosis
- Ist Teil von
- The Journal of infectious diseases, 2005-03, Vol.191 (6), p.985-989
- Ort / Verlag
- Chicago, IL: The University of Chicago Press
- Erscheinungsjahr
- 2005
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Epstein-Barr virus (EBV) DNA loads in peripheral blood mononuclear cells (PBMCs), plasma, and saliva, as well as infectivity of the virus in saliva, were evaluated in 20 patients for 6 months after the onset of infectious mononucleosis (IM). All patients displayed sustained high EBV DNA loads in the saliva, associated with a persistent infectivity of saliva at day 180. EBV DNA load in PBMCs decreased significantly from day 0 to day 180 (in spite of a viral rebound between day 30 and day 90 in 90% of the patients), and EBV DNA rapidly disappeared from plasma. These data show that patients with IM remain highly infectious during convalescence
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-1899eISSN: 1537-6613DOI: 10.1086/428097Titel-ID: cdi_proquest_miscellaneous_67437357
- Format
- –
- Schlagworte
- Adolescent, Adult, Biological and medical sciences, DNA, Viral - blood, Epstein-Barr virus, Female, Fundamental and applied biological sciences. Psychology, Herpesvirus 4, Human - isolation & purification, Herpesvirus 4, Human - pathogenicity, Herpesvirus 4, Human - physiology, Humans, Infectious diseases, Infectious Mononucleosis - virology, Leukocytes, Mononuclear - virology, Male, Medical sciences, Microbiology, Miscellaneous, Saliva - virology, Time Factors, Viral Load, Virology, Virus Shedding