Physical review letters, 2005-01, Vol.94 (3), p.035504.1-035504.4, Article 035504
2005
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Details
- Autor(en) / Beteiligte
- Titel
- Bubble nucleation and cooperativity in DNA melting
- Ist Teil von
- Physical review letters, 2005-01, Vol.94 (3), p.035504.1-035504.4, Article 035504
- Ort / Verlag
- Ridge, NY: American Physical Society
- Erscheinungsjahr
- 2005
- Quelle
- American Physical Society Journals
- Beschreibungen/Notizen
- The onset of intermediate states (denaturation bubbles) and their role during the melting transition of DNA are studied using the Peyrard-Bishop-Dauxois model by Monte Carlo simulations with no adjustable parameters. Comparison is made with previously published experimental results finding excellent agreement. Melting curves, critical DNA segment length for stability of bubbles, and the possibility of a two-state transition are studied.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0031-9007eISSN: 1079-7114DOI: 10.1103/PhysRevLett.94.035504Titel-ID: cdi_proquest_miscellaneous_67413887
- Format
- –
- Schlagworte
- Analytical, structural and metabolic biochemistry, Base Sequence, Biological and medical sciences, Computer Simulation, DNA - analysis, DNA - chemistry, DNA, RNA, Fundamental and applied biological sciences. Psychology, General aspects, investigation methods, Models, Chemical, Models, Molecular, Molecular Sequence Data, Nucleic Acid Conformation, Nucleic Acid Denaturation, Nucleic acids, Phase Transition, Structure-Activity Relationship, Transition Temperature