UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 11 von 13373
Datensatz exportieren als...
BibTeX
Risk of tumour progression in early-stage hepatocellular carcinoma after radiofrequency ablation
British journal of surgery, 2009-07, Vol.96 (7), p.756-762
Fernandes, M. L.
Lin, C.-C.
Lin, C.-J.
Chen, W.-T.
Lin, S.-M.
2009
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Fernandes, M. L.
Lin, C.-C.
Lin, C.-J.
Chen, W.-T.
Lin, S.-M.
Titel
Risk of tumour progression in early-stage hepatocellular carcinoma after radiofrequency ablation
Ist Teil von
British journal of surgery, 2009-07, Vol.96 (7), p.756-762
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2009
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
Background: This study aimed objectively to quantify the risk of tumour progression beyond the Milan criteria following radiofrequency (RF) ablation for hepatocellular carcinoma (HCC) and to identify factors associated with tumour progression. Methods: Some 111 patients (136 tumours) with liver cirrhosis undergoing RF ablation for HCC within Milan criteria between February 2004 and June 2007 were enrolled in the study. Data were analysed retrospectively from a prospectively collected database. Results: The cumulative probability of tumour progression beyond the Milan criteria at 6, 12, 18, 24 and 36 months of RF ablation was 6·4, 11·0, 16·1, 21·2 and 44·8 per cent respectively. On multivariable analysis, factors independently associated with tumour progression were failure to achieve primary technique effectiveness (P = 0·005), α‐fetoprotein level above 200 ng/ml (P = 0·013) and Child–Pugh grade B cirrhosis (P = 0·034). Failure to achieve primary RF ablation technique effectiveness was associated with tumour location in segment VIII (P = 0·033), a cool‐down temperature of 70 °C or less (P = 0·043) and multiple overlapping ablations (P = 0·029). Conclusion: This study provides clinicians with an objective risk of tumour progression beyond the Milan criteria after RF ablation at multiple time points. Primary technique failure is identified as a risk factor for tumour progression. Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Quantifies and stratifies the risk
Sprache
Englisch
Identifikatoren
ISSN: 0007-1323
eISSN: 1365-2168
DOI: 10.1002/bjs.6645
Titel-ID: cdi_proquest_miscellaneous_67395138
Format
–
Schlagworte
Adult
,
Aged
,
Aged, 80 and over
,
alpha-Fetoproteins - metabolism
,
Biological and medical sciences
,
Carcinoma, Hepatocellular - pathology
,
Carcinoma, Hepatocellular - surgery
,
Catheter Ablation - methods
,
Disease Progression
,
Epidemiologic Methods
,
Female
,
Gastroenterology. Liver. Pancreas. Abdomen
,
General aspects
,
Humans
,
Liver. Biliary tract. Portal circulation. Exocrine pancreas
,
Male
,
Medical sciences
,
Middle Aged
,
Neoplasm Recurrence, Local - pathology
,
Risk Factors
,
Severity of Illness Index
,
Treatment Outcome
,
Tumors
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX