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Chembiochem : a European journal of chemical biology, 2009-06, Vol.10 (9), p.1453-1456
Ort / Verlag
Weinheim: Wiley-VCH Verlag
Erscheinungsjahr
2009
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Delivering the goods: By coupling proteins to varyingly sized polymeric microspheres, it is possible to deliver them to cells in an easy and effective way. For this study a fluorescent protein (EGFP) and a functional enzyme (β-galactosidase) were coupled to these particles. Evaluation of the cellular uptake after "beadfection" shows that the functionality and activity of these proteins were not adversely affected through coupling to the carrier system; this shows that their functional structure is retained.