Details

Autor(en) / Beteiligte

• Harned, Andrew M
• He, Helen Song
• Toy, Patrick H
• Flynn, Daniel L
• Hanson, Paul R

Titel

Multipolymer Solution-Phase Reactions: Application to the Mitsunobu Reaction

Ist Teil von

• Journal of the American Chemical Society, 2005-01, Vol.127 (1), p.52-53

Ort / Verlag

Washington, DC: American Chemical Society

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• The realization of the first polymer-on-polymer Mitsunobu reaction, in which a polymeric phosphine is used simultaneously with a polymeric azodicarboxylate, is reported. This strategy employs the use of soluble oligomers generated from ring-opening methathesis polymerization. 31P NMR analysis revealed that the two polymers were interacting to generate the Mitsunobu products. Application to several substrates, as well as comparison experiments with other polymeric reagents, is described.