European journal of pediatrics, 2004-12, Vol.163 (12), p.709-716
2004
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Details
- Autor(en) / Beteiligte
- Titel
- Prospective population-based study of viral lower respiratory tract infections in children under 3 years of age (the PRI.DE study)
- Ist Teil von
- European journal of pediatrics, 2004-12, Vol.163 (12), p.709-716
- Ort / Verlag
- Heidelberg: Springer
- Erscheinungsjahr
- 2004
- Quelle
- SpringerLink
- Beschreibungen/Notizen
- Population-based incidence data from Europe on the disease burden of lower respiratory tract infections (LRTI) due to respiratory syncytial viruses (RSV), parainfluenza viruses (PIV) and influenzaviruses (IV) are lacking, especially with respect to the disease burden. In a 2-year prospective multicentre study of children aged <3 years in Germany, we registered population-based cases as outpatients (n=2386), inpatients (n=2924), and nosocomially-acquired (n=141). Nasopharyngeal secretions were tested for viral RNA. The annual incidence for physician visits per 100 children for all LRTI was 28.7, RSV 7.7, PIV 3.8 and IV 1.1. Annual hospitalisation rates per 10(5) children were for all LRTI 2941, RSV 1117, PIV 261 and IV 123. Annual nosocomial cases per 10(5) hospital days were for all LRTI 79, RSV 29, PIV 9 and IV 1.5. All five children (0.27%) who died had an underlying disease and four were nosocomially acquired. Hospitalisation rates due to lower respiratory tract infections in healthy children were similar to those reported elsewhere; the rates for outpatient visits were approximately ten times higher.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0340-6199eISSN: 1432-1076DOI: 10.1007/s00431-004-1523-9Titel-ID: cdi_proquest_miscellaneous_67277241
- Format
- –
- Schlagworte
- Age groups, Biological and medical sciences, Child, Preschool, Children & youth, Chronic obstructive pulmonary disease, asthma, Consent, Cross Infection - epidemiology, Cross Infection - virology, Female, General aspects, Germany - epidemiology, Hospitalization, Hospitalization - statistics & numerical data, Hospitals, Humans, Incidence, Infant, Infant, Newborn, Infections, Male, Medical sciences, Nasopharynx - virology, Office Visits - statistics & numerical data, Orthomyxoviridae - isolation & purification, Parainfluenza Virus 1, Human - isolation & purification, Parainfluenza Virus 2, Human - isolation & purification, Parainfluenza Virus 3, Human - isolation & purification, Patients, Pediatrics, Pneumology, Population-based studies, Prospective Studies, Respiratory syncytial virus, Respiratory Syncytial Viruses - isolation & purification, Respiratory Tract Infections - epidemiology, Respiratory Tract Infections - virology, RNA, Viral - isolation & purification, Seasons, Testing laboratories, Vaccines, Viruses