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Restless legs syndrome in multiple sclerosis: A case-control study
Movement disorders, 2009-04, Vol.24 (5), p.697-701
Deriu, Marcello
Cossu, Giovanni
Molari, Andrea
Murgia, Daniela
Mereu, Alessandra
Ferrigno, Paola
Manca, Davide
Contu, Paolo
Melis, Maurizio
2009
Details
Autor(en) / Beteiligte
Deriu, Marcello
Cossu, Giovanni
Molari, Andrea
Murgia, Daniela
Mereu, Alessandra
Ferrigno, Paola
Manca, Davide
Contu, Paolo
Melis, Maurizio
Titel
Restless legs syndrome in multiple sclerosis: A case-control study
Ist Teil von
Movement disorders, 2009-04, Vol.24 (5), p.697-701
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2009
Link zum Volltext
Quelle
Wiley Online Library - AutoHoldings Journals
Beschreibungen/Notizen
The aim of our study was to explore restless legs syndrome (RLS) frequency in multiple sclerosis (MS)‐patients and establish whether RLS could be a symptom of MS. Over a period of 1 year, we consecutively enrolled 202 MS‐patients and 212 healthy controls, matched for sex and age, in a case‐control study. All of them filled in a structured questionnaire according to IRLSSG criteria. Those patients who fit the diagnostic criteria were subsequently examined by a neurologist to verify the effective presence of RLS. A total of 91 MS‐patients (45%) responded positively to the questionnaires. The diagnosis of RLS was carried out in 29subjects (14.4%). Among the healthy controls, a definite diagnosis of RLS was achieved only in 6 subjects (2.8%). The risk of MS patients to present RLS was significantly higher (OR.5.76 P:0.00002) than the general population. None of them was affected by other medical conditions related to RLS developing. The 62 remaining patients presented numbness and weakness of the legs not suggestive of RLS. Our findings confirm a significant correlation between MS and RLS. In our opinion, MS must be definitively included among RLS causes. © 2008 Movement Disorder Society
Sprache
Englisch
Identifikatoren
ISSN: 0885-3185
eISSN: 1531-8257
DOI: 10.1002/mds.22431
Titel-ID: cdi_proquest_miscellaneous_67193451
Format
–
Schlagworte
Adult
,
Biological and medical sciences
,
Case-Control Studies
,
Disability Evaluation
,
Female
,
Humans
,
Male
,
Medical sciences
,
Middle Aged
,
multiple sclerosis
,
Multiple Sclerosis - complications
,
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
,
Neurology
,
prevalence
,
Restless Legs Syndrome - etiology
,
Retrospective Studies
,
RLS
,
Severity of Illness Index
,
Surveys and Questionnaires
,
symptomatic
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