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Faecal occult blood test-based screening programme with high compliance for colonoscopy has a strong clinical impact on colorectal cancer
British journal of surgery, 2009-05, Vol.96 (5), p.533-540
Parente, F.
Marino, B.
DeVecchi, N.
Moretti, R.
2009
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Parente, F.
Marino, B.
DeVecchi, N.
Moretti, R.
Titel
Faecal occult blood test-based screening programme with high compliance for colonoscopy has a strong clinical impact on colorectal cancer
Ist Teil von
British journal of surgery, 2009-05, Vol.96 (5), p.533-540
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2009
Quelle
Wiley Blackwell Single Titles
Beschreibungen/Notizen
Background: The results of a pilot colorectal cancer screening programme by biennial immunochemical faecal occult blood test (FOBT) are reported. Methods: All residents aged between 50 and 69 years in the Italian province of Lecco were invited to have a FOBT. Those with a positive result were offered colonoscopy. FOBT uptake and compliance with colonoscopy were assessed. Detection rate and positive predictive value (PPV) for cancer and adenoma were calculated. Tumour stages were compared between screen‐detected cancers and other colorectal cancers diagnosed within the target age group. Results: Some 38 693 (49·6 per cent) of 78 083 individuals had a FOBT and 2392 (6·2 per cent) had a positive result. Colorectal cancer was diagnosed in 4·6 per cent and advanced adenoma in 32·7 per cent. PPVs were 4·0 per cent for cancer, 28·1 per cent for advanced adenoma and 36·6 per cent for any adenoma. There was a significant difference in incidence of stage III/IV disease between screened and non‐screened cohorts. Compliance for colonoscopy was 92·0 per cent. Major determinants of compliance were age less than 59 years, female sex, high education level and non‐manual work. Conclusion: These results justify extension of colorectal cancer screening to other regions of Italy. Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Results from a regional programme
Sprache
Englisch
Identifikatoren
ISSN: 0007-1323
eISSN: 1365-2168
DOI: 10.1002/bjs.6568
Titel-ID: cdi_proquest_miscellaneous_67124362
Format
–
Schlagworte
Aged
,
Aged, 80 and over
,
Biological and medical sciences
,
Colonoscopy - statistics & numerical data
,
Colorectal Neoplasms - diagnosis
,
Early Detection of Cancer
,
Educational Status
,
Female
,
General aspects
,
Humans
,
Italy
,
Male
,
Mass Screening - methods
,
Medical sciences
,
Middle Aged
,
Occult Blood
,
Patient Compliance - statistics & numerical data
,
Pilot Projects
,
Prevention and actions
,
Public health. Hygiene
,
Public health. Hygiene-occupational medicine
,
Sex Distribution
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