Clinical cancer research, 2009-02, Vol.15 (3), p.749-751
2009
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Details
- Autor(en) / Beteiligte
- Titel
- Overcoming Cancer Immune Tolerance and Escape
- Ist Teil von
- Clinical cancer research, 2009-02, Vol.15 (3), p.749-751
- Ort / Verlag
- United States: American Association for Cancer Research
- Erscheinungsjahr
- 2009
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Although HER2/neu–targeted cancer vaccines have shown initial promise in the adjuvant setting, a therapeutic vaccine remains elusive due to the tumor escape mechanisms of established cancer. As described by Seavey et al. in this issue of CCR, a Listeria -delivered vaccine may help overcome immune tolerance, leading to an effective therapeutic vaccine.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1078-0432eISSN: 1557-3265DOI: 10.1158/1078-0432.CCR-08-2805Titel-ID: cdi_proquest_miscellaneous_66879556
- Format
- –
- Schlagworte
- Adjuvants, Immunologic, Animals, Bacterial Toxins - therapeutic use, Breast Cancer, Cancer Vaccines - therapeutic use, Clinical Trials as Topic, Genes, erbB-2, Genetic Vectors, Heat-Shock Proteins - therapeutic use, Hemolysin Proteins - therapeutic use, Humans, Immune Tolerance, Listeria, Listeria monocytogenes - immunology, Mice, Models, Biological, Neoplasms - immunology, Tumor Escape, Vaccine, Vaccines, Synthetic - therapeutic use