Details

Autor(en) / Beteiligte

• Chang, Lynne
• Goldman, Robert D

Titel

Intermediate filaments mediate cytoskeletal crosstalk

Ist Teil von

• Nature reviews. Molecular cell biology, 2004-08, Vol.5 (8), p.601-613

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2004

Quelle

MEDLINE

Beschreibungen/Notizen

• Intermediate filaments, actin-containing microfilaments and microtubules are the three main cytoskeletal systems of vertebrate and many invertebrate cells. Although these systems are composed of distinctly different proteins, they are in constant and intimate communication with one another. Understanding the molecular basis of this cytoskeletal crosstalk is essential for determining the mechanisms that underlie many cell-biological phenomena. Recent studies have revealed that intermediate filaments and their associated proteins are important components in mediating this crosstalk.