Nature reviews. Genetics, 2009-02, Vol.10 (2), p.141-148
2009
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Details
- Autor(en) / Beteiligte
- Titel
- The evolution of hierarchical gene regulatory networks
- Ist Teil von
- Nature reviews. Genetics, 2009-02, Vol.10 (2), p.141-148
- Ort / Verlag
- London: Nature Publishing Group
- Erscheinungsjahr
- 2009
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Comparative developmental evidence indicates that reorganizations in developmental gene regulatory networks (GRNs) underlie evolutionary changes in animal morphology, including body plans. We argue here that the nature of the evolutionary alterations that arise from regulatory changes depends on the hierarchical position of the change within a GRN. This concept cannot be accomodated by microevolutionary nor macroevolutionary theory. It will soon be possible to investigate these ideas experimentally, by assessing the effects of GRN changes on morphological evolution.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1471-0056eISSN: 1471-0064DOI: 10.1038/nrg2499Titel-ID: cdi_proquest_miscellaneous_66830235
- Format
- –
- Schlagworte
- Biological and medical sciences, Biological Evolution, Circuits, Evolution, Fundamental and applied biological sciences. Psychology, Gene expression, Gene Expression Regulation, Developmental, Gene Regulatory Networks - genetics, Genes, Genetic aspects, Genetic regulation, Genetics of eukaryotes. Biological and molecular evolution, Insects, Macroevolution, Models, Genetic, Morphogenesis - genetics, Morphology, Morphology (Animals), Mutation, Transcription factors