Details

Autor(en) / Beteiligte

• Tonino, Pim A.L
• De Bruyne, Bernard
• Pijls, Nico H.J
• Siebert, Uwe
• Ikeno, Fumiaki
• van `t Veer, Marcel
• Klauss, Volker
• Manoharan, Ganesh
• Engstrøm, Thomas
• Oldroyd, Keith G
• Ver Lee, Peter N
• MacCarthy, Philip A
• Fearon, William F

Titel

Fractional Flow Reserve versus Angiography for Guiding Percutaneous Coronary Intervention

Ist Teil von

• The New England journal of medicine, 2009-01, Vol.360 (3), p.213-224

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• Fractional flow reserve (FFR) is a measure of the functional significance of a coronary stenosis. In this study, the use of FFR, as compared with angiography alone, in guiding the placement of coronary stents resulted in the use of fewer stents and better clinical outcomes. The use of fractional flow reserve, as compared with coronary angiography alone, in guiding the placement of coronary stents resulted in the use of fewer stents and better clinical outcomes. The presence of myocardial ischemia is an important risk factor for an adverse clinical outcome. 1 – 3 Revascularization of stenotic coronary lesions that induce ischemia can improve a patient's functional status and outcome. 3 – 5 For stenotic lesions that do not induce ischemia, however, the benefit of revascularization is less clear, and medical therapy alone is likely to be equally effective. 6 , 7 With the introduction of drug-eluting stents, the percentage of patients with multivessel coronary artery disease in whom percutaneous coronary intervention (PCI) is performed has increased. 8 , 9 Because drug-eluting stents are expensive and are associated with potential late complications, their appropriate . . .