FEMS Immunology and Medical Microbiology, 2004-09, Vol.42 (1), p.48-52
2004
Details
- Autor(en) / Beteiligte
- Titel
- IL-10 gene polymorphisms in infectious disease and SIDS
- Ist Teil von
- FEMS Immunology and Medical Microbiology, 2004-09, Vol.42 (1), p.48-52
- Ort / Verlag
- Oxford, UK: Elsevier B.V
- Erscheinungsjahr
- 2004
- Link zum Volltext
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Interleukin-10 (IL-10) is a regulatory cytokine, and its principal role in vivo is to limit inflammatory response. IL-10 has been shown to influence both the susceptibility and course of various diseases, and the different polymorphisms in the IL-10 gene promoter have been associated with disease prevalence and severity. The genes involved in the immune system are also assumed to be of importance with regard to sudden infant death syndrome (SIDS), and specific haplotypes in the IL-10 gene promoter have been reported associated both with SIDS and sudden unexpected death due to infection.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0928-8244eISSN: 1574-695X, 2049-632XDOI: 10.1016/j.femsim.2004.06.006Titel-ID: cdi_proquest_miscellaneous_66805043
- Format
- –
- Schlagworte
- Gene polymorphism, Genetic Predisposition to Disease, Haplotypes, Humans, Immune system, Infant, Infection, Infection - genetics, Infectious diseases, Inflammation, Inflammatory response, Interleukin 10, Interleukin-10 - genetics, Polymorphism, Genetic, SIDS, Sudden Infant Death - genetics, Sudden infant death syndrome