Details

Autor(en) / Beteiligte

• Campeau, Louis-Charles
• Parisien, Mathieu
• Leblanc, Melissa
• Fagnou, Keith

Titel

Biaryl Synthesis via Direct Arylation:  Establishment of an Efficient Catalyst for Intramolecular Processes

Ist Teil von

• Journal of the American Chemical Society, 2004-08, Vol.126 (30), p.9186-9187

Ort / Verlag

Washington, DC: American Chemical Society

Erscheinungsjahr

2004

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this Communication, we describe direct arylation reactions with improved scope and catalyst activity for the intramolecular formation of biaryl compounds. This was achieved through the establishment of a highly active and robust catalyst system and the subsequent development of a novel phosphine ligand 27. The enhanced catalytic activity extends these transformations to include previously unreactive and poorly reactive substrates, and allows for very low catalyst loadings to be employedas little as 0.1 mol %.