Details

Autor(en) / Beteiligte

• Østerdal, ML
• Strøm, M
• Klemmensen, ÅK
• Knudsen, VK
• Juhl, M
• Halldorsson, TI
• Nybo Andersen, A‐M
• Magnus, P
• Olsen, SF

Titel

Does leisure time physical activity in early pregnancy protect against pre‐eclampsia? Prospective cohort in Danish women

Ist Teil von

• BJOG : an international journal of obstetrics and gynaecology, 2009-01, Vol.116 (1), p.98-107

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

2009

Quelle

Access via Wiley Online Library

Beschreibungen/Notizen

• Objective  To examine the association between physical activity in early pregnancy and risk of pre‐eclampsia. Design  Prospective cohort. Setting  Denmark. Population  A total of 85 139 pregnant Danish women, recruited between 1996 and 2002. Methods  The authors assessed leisure time physical activity in first trimester by a telephone interview and categorised women a priori into seven groups: 0 (reference), 1–44, 45–74, 75–149, 150–269, 270–419 and 420+ minutes/week. Pre‐eclampsia diagnoses were extracted from the Danish National Patient Registry. A number of potential confounders were adjusted for by logistic regression. Main outcome measures  Pre‐eclampsia and severe pre‐eclampsia. Results  The two highest physical activity levels were associated with increased risk of severe pre‐eclampsia compared with the nonexercising group, with adjusted odds ratios of 1.65 (95% CI: 1.11–2.43) and 1.78 (95% CI: 1.07–2.95), whereas more moderate levels of physical activity (1–270 minutes/week) had no statistically significant association with risk of pre‐eclampsia (total n = 85 139). Conclusions  We were unable to document a protective effect of leisure time physical activity against pre‐eclampsia. Our data even suggest that leisure time physical activity exceeding 270 minutes/week in first trimester may increase risk of severe pre‐eclampsia.