Details

Autor(en) / Beteiligte

• Muñoz Javier, Alumdena
• Kreft, Oliver
• Semmling, Maximilian
• Kempter, Susanne
• Skirtach, Andre G.
• Bruns, Oliver T.
• del Pino, Pablo
• Bedard, Mathieu F.
• Rädler, Joachim
• Käs, Josef
• Plank, Christian
• Sukhorukov, Gleb B.
• Parak, Wolfgang J.

Titel

Uptake of Colloidal Polyelectrolyte‐Coated Particles and Polyelectrolyte Multilayer Capsules by Living Cells

Ist Teil von

• Advanced materials (Weinheim), 2008-11, Vol.20 (22), p.4281-4287

Ort / Verlag

Weinheim: WILEY‐VCH Verlag

Erscheinungsjahr

2008

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Rigid particles as well as soft capsules can be ingested by cells and stored in acidic compartments around the nucleus. TEM and fluorescence images show that the rigid particles retain their original spherical shape whereas the hollow and thus more flexible capsules are deformed and squeezed upon the incorporation process. Though soft capsules are deformed upon uptake, the cargo loaded into the capsules is not released into the cytosol.