Details

Autor(en) / Beteiligte

• Manabe, Yoshiyuki
• Tsutsui, Yuya
• Tanaka, Yosuke
• Yokoyama, Yuka
• Ikinaga, Yuka
• Nishitani, Tatsuya
• Yano, Kumpei
• Miyagawa, Ryohei
• Fukase, Koichi
• Konishi, Akihito
• Yasuda, Makoto

Titel

Cage-Shaped Borate Catalysts Bearing Precisely Controlled Lewis Acidity and Their Application in Glycosylations

Ist Teil von

• Journal of organic chemistry, 2024-11, Vol.89 (21), p.15630

Ort / Verlag

United States

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Cage-shaped borates, whose Lewis acidity can be precisely modulated by the structural attributes of the triphenolic ligands, were employed as catalysts for glycosylation. Each cage-shaped borate displayed distinctive reactivity; thus, screening of the borate catalysts enabled controllable activation of glycosyl fluorides under mild conditions. Practical glycosylation was achieved by fine-tuning the Lewis acidity tailored to the substrate reactivity, thereby providing a versatile method applicable to the synthesis of complex glycans.