Details

Autor(en) / Beteiligte

• O'Connor, Madeline J.
• Bartler, Angelica V.
• Ho, Kelly C.
• Zhang, Kenneth
• Casas Fuentes, Rolando J.
• Melnick, Bradley A.
• Huffman, Kristin N.
• Hong, Seok Jong
• Galiano, Robert D.

Titel

Understanding Staphylococcus aureus in hyperglycaemia: A review of virulence factor and metabolic adaptations

Ist Teil von

• Wound repair and regeneration, 2024-06

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Abstract Staphylococcus aureus is one of the most commonly detected bacteria in diabetic skin and soft tissue infections. The incidence and severity of skin and soft tissue infections are higher in patients with diabetes, indicating a potentiating mechanism of hyperglycaemia and infection. The goal of this review is to explore the metabolic and virulence factor adaptations of S. aureus under hyperglycaemic conditions. Primary data from identified studies were included and summarised in this paper. Understanding the nexus of hyperglycaemia, metabolism, and virulence factors provides insights into the complexity of diabetic skin and soft tissue infections attributed to S. aureus.