Details

Autor(en) / Beteiligte

• Yong, Heather Y.F.
• Batty, Nicholas J.
• Tottenham, Isabelle
• Koch, Marcus
• Camara-Lemarroy, Carlos R.

Titel

Soluble adhesion molecules: Cognitive worsening biomarkers in primary progressive multiple sclerosis?

Ist Teil von

• Journal of neuroimmunology, 2024-08, Vol.393, p.578384, Article 578384

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• [Display omitted] •Soluble adhesion markers may represent cognitive biomarkers in multiple sclerosis•Soluble NCAM-1 and VCAM-1 are elevated in primary progressive multiple sclerosis•Cognitive worsening in PPMS is associated with higher baseline VCAM-1 levels•Each 100 ng/mL VCAM-1 increase carries a 30% increased odds of cognitive worsening•Lower baseline BDNF is associated with lower baseline cognitive scores in PPMS