Details

Autor(en) / Beteiligte

• Harikrishnan, Thilagam
• Paramasivam, Pandi
• Sankar, Anusuya
• Sakthivel, Madhavan
• Sanniyasi, Elumalai
• Raman, Thiagarajan
• Thangavelu, Muthukumar
• Singaram, Gopalakrishnan
• Muthusamy, Govarthanan

Titel

Weathered polyethylene microplastics induced immunomodulation in zebrafish

Ist Teil von

• Environmental toxicology and pharmacology, 2024-08, Vol.109, p.104478, Article 104478

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Microplastics are pollutants of emerging concern and the aquatic biota consumes microplastics (MPs), which has a range of toxicological and environmental effects on aquatic organisms that are not the intended targets. The current study looked into how weathered polyethylene (wPE) MPs affected Danio albolineatus immunological and haematological markers. In this experiment, fish of both sexes were placed in control and exposure groups, and they were exposed for 40 d at the sublethal level (1 μg L-1) of fragmented wPE, which contained 1074 ± 52 MPs per litre. Similarly, fish exposed to wPE MPs showed significant modifications in lysozyme, antimicrobial, and antiprotease activity, as well as differential counts. Results of the present study show that the male fish were more susceptible than female fish after 40 d of chronic exposure. Further studies are needed to ascertain how the innate and humoral immune systems of the fish respond to MPs exposure. •wPE microplastic exposure leads to haematological changes in zebrafish.•wPE microplastics exposure modulates innate immune response in zebrafish.•wPE microplastic exposure caused sex specific responses in zebrafish.•wPE microplastic induced immune modulation could affect health and survivability of zebrafish