Details

Autor(en) / Beteiligte

• Zhang, Geng-Si
• Li, Hai-Yan
• Liang, Li-Fen
• Fu, Chun-Qing
• Yu, Qin
• Liu, Kai
• Su, Zhi-Wei
• Zhou, Dong-Mei
• Gao, Cheng-Hai
• Xu, Xin-Ya
• Liu, Yong-Hong

Titel

Secofumitremorgins C and D, a pair of atropisomers from saltern-derived fungus Aspergillus fumigatus GXIMD00544

Ist Teil von

• Journal of asian natural products research, 2024-09, Vol.26 (9), p.1049-1056

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A pair of atropisomers secofumitremorgins C (1a) and D (1b), together with fifteen known alkaloids (2-16), were isolated from a saltern-derived fungus Aspergillus fumigatus GXIMD00544. The structures of atropisomers 1a and 1b were elucidated by the detailed spectroscopic data, chemical reaction and quantum chemical calculations. Compounds 1 and 8 displayed antifungal spore germination effects against plant pathogenic fungus associated with sugarcane Fusarium sp. with inhibitory rates of 53% and 77% at the concentration of 100 µM, repectively. Atropisomers 1 also exhibited antifouling potential against Balanus amphitrite larval settlement with an inhibitory rate of 96% at the concentration of 100 µM.