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Exploring the impact of music on response to ketamine/esketamine: A scoping review
Ist Teil von
Neuroscience and biobehavioral reviews, 2024-07, Vol.162, p.105693-105693, Article 105693
Ort / Verlag
United States: Elsevier Ltd
Erscheinungsjahr
2024
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Music and ketamine are both known to affect therapeutic outcomes, but few studies have investigated their co-administration. This scoping review describes the existing literature on the joint use of music and ketamine—or esketamine (the S(+) enantiomer of ketamine)—in humans. The review considers that extant studies have explored the intersection of ketamine/esketamine and music in healthy volunteers and in patients of various age groups, at different dosages, through different treatment processes, and have varied the sequence of playing music relative to ketamine/esketamine administration. Studies investigating the use of music during ketamine anesthesia are also included in the review because anesthesia and sedation were the early drivers of ketamine use. Studies pertaining to recreational ketamine use were omitted. The review was limited to articles published in the English language but not restricted by publication year. To the best of our knowledge, this scoping review is the first comprehensive exploration of the interplay between music and ketamine/esketamine and offers valuable insights to researchers interested in designing future studies.
•The co-administration of music and ketamine has rarely been explored.•With ketamine alone, music reduces dissociation and anxiety and boosts tolerability.•In combination drug studies, music promotes relaxation and reduces sedative load.•Patient-specific factors influence how music impacts response to ketamine.