Details

Autor(en) / Beteiligte

• Vera-Duarte, Guillermo Raul
• Jimenez-Collado, David
• Kahuam-López, Nicolás
• Ramirez-Miranda, Arturo
• Graue-Hernandez, Enrique O.
• Navas, Alejandro
• Rosenblatt, Mark I

Titel

Neurotrophic keratopathy: General features and new therapies

Ist Teil von

• Survey of ophthalmology, 2024-04

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• Neurotrophic keratopathy is an uncommon degenerative corneal disorder characterized by compromised corneal sensory innervation, resulting in the formation of epithelial defects and nonhealing corneal ulcers. Various treatment modalities are available to stabilize disease progression, improve patient well-being, and prevent vision loss. For eligible patients, medical and surgical reinnervation have emerged as pioneering therapies, holding promise for better management. This article presents a comprehensive review of the disease, providing an update relevant to ophthalmologists on pathogenesis, diagnosis, treatment options, and novel therapies targeting pathophysiological pathways.