Chemical communications (Cambridge, England), 2024-05, Vol.6 (4), p.5322-5325
2024
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- Autor(en) / Beteiligte
- Titel
- An NIR-II-emitting type-I photosensitizer for efficient hypoxic tumor phototheranostics
- Ist Teil von
- Chemical communications (Cambridge, England), 2024-05, Vol.6 (4), p.5322-5325
- Ort / Verlag
- England: Royal Society of Chemistry
- Erscheinungsjahr
- 2024
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A small molecule-based NIR-II type-I photosensitizer (IT-IC) with a strong push-pull effect and good planar π-conjugated structure was synthesized. The IT-IC NPs exhibited strong light absorption, outstanding NIR-II fluorescence emission, excellent photothermal conversion and efficient type-I/II ROS generation, showing encouraging therapeutic outcomes for hypoxic tumors. An NIR-II-emitting type-I photosensitizer with a strong push-pull effect and good planar π-conjugated structure was synthesized for efficient hypoxic tumor phototheranostics.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1359-7345eISSN: 1364-548XDOI: 10.1039/d4cc00431kTitel-ID: cdi_proquest_miscellaneous_3047944259
- Format
- –
- Schlagworte
- Animals, Antineoplastic Agents - chemical synthesis, Antineoplastic Agents - chemistry, Antineoplastic Agents - pharmacology, Cell Line, Tumor, Cell Survival - drug effects, Electromagnetic absorption, Humans, Infrared Rays, Mice, Molecular Structure, Nanoparticles - chemistry, Neoplasms - drug therapy, Neoplasms - pathology, Photochemotherapy, Photosensitizing Agents - chemical synthesis, Photosensitizing Agents - chemistry, Photosensitizing Agents - pharmacology, Photothermal conversion, Reactive Oxygen Species - metabolism, Theranostic Nanomedicine, Tumor Hypoxia - drug effects, Tumors