Details

Autor(en) / Beteiligte

• Yıldız, Mustafa
• Güner, Ahmet
• Demirci, Gökhan
• Çizgeci, Ahmet Yaşar
• Kahraman, Serkan
• Barman, Hasan Ali
• Uzun, Fatih
• Akman, Cemalettin
• Aydın, Emre
• Doğan, Abdullah
• Türkmen, İrem
• Yıldız, Muhammed Mustafa
• Ertürk, Mehmet

Titel

Long-term outcomes following double kissing crush or mini-culotte stenting for complex coronary bifurcation lesions: the EVOLUTE-CRUSH IV study

Ist Teil von

• Herz, 2024-10, Vol.49 (5), p.361-370

Ort / Verlag

Heidelberg: Springer Medizin

Erscheinungsjahr

2024

Quelle

SpringerLink

Beschreibungen/Notizen

• Background This study aimed to evaluate the long-term outcomes of double kissing crush stenting (DKC) and mini-culotte technique (MCT) in patients with complex bifurcation lesions. Methods This retrospective study enrolled 236 patients who underwent percutaneous coronary intervention (PCI) for complex coronary bifurcation disease between January 2014 and November 2022. The primary endpoint was target lesion failure (TLF), defined as the combination of cardiac death, myocardial infarction (MI), or clinically driven target lesion revascularization (TLR). The secondary endpoint was major cardiovascular and cerebral events (MACCE) including all-cause death, MI, TLR, stroke, or stent thrombosis. The regression models were adjusted by applying the inverse probability weighted (IPW) approach to reduce treatment selection bias. Results The initial management strategy was DKC in 154 (65.3%) patients and MCT in 82 (34.7%) patients (male: 194 [82.2%], mean age: 60.85 ± 10.86 years). The SYNTAX scores were similar in both groups. The rates of long-term TLF and MACCE rates were 17.4% and 20%, respectively. The rate of TLF (26.8% vs. 12.3%, p  = 0.005) was higher in patients treated with MCT than those treated with the DKC technique, mainly driven by more frequent TLR (15.9% vs. 7.1%, p  = 0.035). The long-term TLF and MACCE rates were notably lower in the DKC group compared to the others: adjusted hazard ratio (HR; IPW): 0.407, p  = 0.009 for TLF, and adjusted HR(IPW): 0.391 [95% CI: 0.209–0.730], p  = 0.003 for MACCE. Conclusion At long-term follow-up, the rates of TLF and MACCE were 17.4% and 20%, respectively. However, long-term TLF was significantly higher in patients treated with MCT than those treated with the DKC technique, primarily due to a more frequent occurrence of clinically driven TLR.