Details

Autor(en) / Beteiligte

• Ran, Kathleen R.
• Das, Oishika
• Johnston, David T.
• Vutakuri, Neha
• Ranganathan, Sruthi
• Broachwala, Mustafa
• Chopra, Harman
• Long Azad, Chao
• Azad, Tej D.
• Robinson, Shenandoah
• Belzberg, Allan J.
• Tuffaha, Sami H.
• Lubelski, Daniel

Titel

Nerve-Targeted Surgical Treatments for Spasticity: A Narrative Review

Ist Teil von

• World neurosurgery, 2024-07, Vol.187, p.104-113

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Spasticity is a potentially debilitating symptom of various acquired and congenital neurologic pathologies that, without adequate treatment, may lead to long-term disability, compromise functional independence, and negatively impact mental health. Several conservative as well as non-nerve targeted surgical strategies have been developed for the treatment of spasticity, but these may be associated with significant drawbacks, such as adverse side effects to medication, device dependence on intrathecal baclofen pumps, and inadequate relief with tendon-based procedures. In these circumstances, patients may benefit from nerve-targeted surgical interventions such as (i) selective dorsal rhizotomy, (ii) hyperselective neurectomy, and (iii) nerve transfer. When selecting the appropriate surgical approach, preoperative patient characteristics, as well as the risks and benefits of nerve-targeted surgical intervention, must be carefully evaluated. Here, we review the current evidence on the efficacy of these nerve-targeted surgical approaches for treating spasticity across various congenital and acquired neurologic pathologies.