Details

Autor(en) / Beteiligte

• Zhang, Xia
• Huang, Lei
• Tang, Yu-Jun
• Hu, Ya-Lin
• Xu, Wei
• Li, Hong-Yu
• Zhang, Yu-Bo
• Zhang, Xiao-Qi
• Zhou, Guang-Xiong

Titel

Two new chemical constituents from the aerial parts of Tripterygium wilfordii

Ist Teil von

• Natural product research, 2024-04, p.1-8

Ort / Verlag

England

Erscheinungsjahr

2024

Quelle

Taylor & Francis

Beschreibungen/Notizen

• has been historically employed as a conventional botanical insecticide and a plant of medicinal significance. A new dihydroagarofuran sesquiterpene ( ) and a new acyclic compound ( ), along with seven known compounds ( ), have been isolated from the aerial parts of . The identification of the structures of novel compounds were accomplished through comprehensive spectroscopic analyses, encompassing HRESIMS, NMR, UV, IR, and a comparative analysis with spectroscopic data from compounds previously characterised. In - bioassay, compound exhibited significant inhibitory activity for NO release in LPS-induced RAW 264.7 cells, with an IC value of 15.7  M.