Details

Autor(en) / Beteiligte

• Chen, Guanru
• Chu, Fengjian
• Zhang, Shuheng
• Li, Wangyu
• Zhou, Shiwen
• Wei, Wei
• Chen, Weiwei
• Wang, Xiaozhi
• Yue, Lei
• Feng, Hongru
• Cui, Yanli
• Pan, Yuanjiang

Titel

Ortho C–H Bond Activations in an Atmospheric Microwave Plasma Ion Source

Ist Teil von

• Journal of the American Society for Mass Spectrometry, 2024-05, Vol.35 (5), p.951-959

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• C–H bond ortho-substitution reaction has always been a significant and challenging topic in organic chemistry. We proposed a synthesis method based on microwave plasma torches. High-resolution mass spectrometry was used to monitor rapid reaction products. 2-Alkylbenzimidazole can be formed through the reaction of phenylnitrenium ion and nitriles on a millisecond scale. This reaction can achieve the one-step formation of benzimidazoles from benzene ring single-substituted compounds without the addition of external oxidants or catalysts. A similar C–H bond activation reaction can be accomplished with ketones. Meanwhile, the microwave plasma reactor was modified, and the resulting 2-methylbenzimidazole was successfully collected, indicating the device has good application potential in organic reactions such as C–H bond activation reaction.