Details

Autor(en) / Beteiligte

• Bobadilla-Rosado, Luis O.
• Anaya-Ayala, Javier E.
• Bonilla, Aliberth
• Mier y Teran-Ellis, Santiago
• Miranda-Ramirez, Montserrat
• Laparra-Escareno, Hugo
• Mendez-Dominguez, Nina
• Hinojosa, Carlos A.

Titel

Fifteen Years of Experience with Surgical Management of Bilateral Non-familial Carotid Body Tumors

Ist Teil von

• Annals of vascular surgery, 2024-08, Vol.105, p.60-66

Ort / Verlag

Netherlands: Elsevier Inc

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Bilateral carotid body tumors (CBTs) clinical manifestation is infrequent. We conducted this work to describe our experience in the surgical treatment of bilateral CBT and to analyze our results. A retrospective, observational study. We analyzed the totality of bilateral CBT resections that had been performed in our institution from January 2008 to September 2023. Data was obtained from medical records and anonymized, ethics approval was obtained from our institution committee. As the number of observations was less than those required by the central limit theorem our sample was considered nonparametric. Statistical analysis was performed on Stata 17. We evaluated 16 patients with a total of 32 CBT; surgical resection was performed in 28 cases (87.50%). Median age of the patients was 60 years (interquartile range [IQR] 46–64). Regarding the Shamblin classification, 9 CBTs (32.14%) were classified as Shamblin I, 11 (39.29%) as Shamblin II, and 8 (28.57%) as Shamblin III. The median Distance to the Base of the Skull (DTBOS) was 3.5 cm (IQR 2.7–5.1), and the median tumor volume was 11.25 cc (IQR 3.4–18.7). The median bleeding volume was 300 ml (IQR 200–500), and the median surgical time was 190 min (IQR 145–240). All surgeries were performed using the Retrocarotid Dissection technique. We documented 9 (32.14%) cases of nerve injuries, all of which were transitory. In the median regression a statistically significant association was found between DTBOS, Shamblin classification and tumor volume with intraoperative bleeding and length of stay. Surgical treatment remains safe and should be considered the gold standard for accurate histologic diagnosis. DTBOS and tumor volume, in addition to Shamblin classification, must be considered in preoperative planning to predict bleeding and hospital stay. •The current work is the largest series of bilateral nonfamilial carotid body tumors.•Surgical experience in their management remains scarce.•Surgical treatment is safe and should be considered the gold standard for accurate cytologic diagnosis.