Details

Autor(en) / Beteiligte

• Fukumoto, Yoshihiro
• Tada, Takeshi
• Suzuki, Hideaki
• Nishimoto, Yuji
• Moriuchi, Kenji
• Arikawa, Takuo
• Adachi, Hitoshi
• Momomura, Shin-ichi
• Seino, Yoshihiko
• Yasumura, Yoshio
• Yokoyama, Hiroyuki
• Hiasa, Go
• Hidaka, Takayuki
• Nohara, Shoichiro
• Okayama, Hideki
• Tsutsui, Hiroyuki
• Kasai, Takatoshi
• Takata, Yoshifumi
• Enomoto, Mika
• Saigusa, Yusuke
• Yamamoto, Kouji
• Kinugawa, Koichiro
• Kihara, Yasuki
• on behalf of the SAVIOR-L Investigators

Titel

Chronic Effects of Adaptive Servo-Ventilation Therapy on Mortality and the Urgent Rehospitalization Rate in Patients Experiencing Recurrent Admissions for Heart Failure　― A Multicenter Prospective Observational Study (SAVIOR-L)

Ist Teil von

• Circulation Journal, 2024/04/25, Vol.88(5), pp.692-702

Ort / Verlag

Japan: The Japanese Circulation Society

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Background: This study investigated whether the chronic use of adaptive servo-ventilation (ASV) reduces all-cause mortality and the rate of urgent rehospitalization in patients with heart failure (HF).Methods and Results: This multicenter prospective observational study enrolled patients hospitalized for HF in Japan between 2019 and 2020 who were treated either with or without ASV therapy. Of 845 patients, 110 (13%) received chronic ASV at hospital discharge. The primary outcome was a composite of all-cause death and urgent rehospitalization for HF, and was observed in 272 patients over a 1-year follow-up. Following 1:3 sequential propensity score matching, 384 patients were included in the subsequent analysis. The median time to the primary outcome was significantly shorter in the ASV than in non-ASV group (19.7 vs. 34.4 weeks; P=0.013). In contrast, there was no significant difference in the all-cause mortality event-free rate between the 2 groups.Conclusions: Chronic use of ASV did not impact all-cause mortality in patients experiencing recurrent admissions for HF.