Details

Autor(en) / Beteiligte

• Lamberti, Mary Jo
• Dirks, Abigail
• Kikuchi, Nicholas
• Patel Cervantes, Neha
• Getz, Kenneth

Titel

Benchmarking Site Activation and Patient Enrollment

Ist Teil von

• Therapeutic innovation & regulatory science, 2024-07, Vol.58 (4), p.696-703

Ort / Verlag

Cham: Springer International Publishing

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Clinical trial conduct poses numerous challenges, many pertaining to patient recruitment. The primary objectives of this study were to update benchmarks on site activation and patient enrollment gathered in previous Tufts CSDD studies and examine current usage of recruitment and retention tactics. The data collection focused on site activation and patient enrollment metrics used for studies. Analyses were conducted comparing results from 2012, 2019 and 2023. The results indicate that actual enrollments exceeded planned enrollments for a majority of studies and timelines were shorter than expected. In addition, differences were found for enrollment achievement by global region and site type. Further investigation into studies conducted during a later time frame and post-pandemic could be compared with current benchmarks to examine differences.