Details

Autor(en) / Beteiligte

• Zeng, Chun‐Mei
• Luo, Song‐Yu
• Wang, Xiao
• Cao, Feng‐Lin
• Zhang, Ze‐Sheng
• Zhang, Wen‐Hua
• Dai, Chun‐Lei
• Young, David J.

Titel

A Porphyrin‐Based 3D Metal‐Organic Framework Featuring [Cu8Cl6]10+ Cluster Secondary Building Units: Synthesis, Structure Elucidation, Anion Exchange, and Peroxidase‐Like Activity

Ist Teil von

• Chemistry, an Asian journal, 2024-05, Vol.19 (10), p.e202400237-n/a

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2024

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Herein, we report a rare example of cationic three‐dimensional (3D) metal‐organic framework (MOF) of [Cu5Cl3(TMPP)]Cl5 ⋅ xSol (denoted as Cu−TMPP; H2TMPP=meso‐tetrakis (6‐methylpyridin‐3‐yl) porphyrin; xSol=encapsulated solvates) supported by [Cu8Cl6]10+ cluster secondary building units (SBUs) wherein the eight faces of the Cl−‐based octahedron are capped by eight Cu2+. Surface‐area analysis indicated that Cu−TMPP features a mesoporous structure and its solvate‐like Cl− counterions can be exchanged by BF4−, PF6−, and NO3−. The polyvinylpyrrolidone (PVP) coated Cu−TMPP (denoted as Cu−TMPP−PVP) demonstrated good ROS generating ability, producing ⋅OH in the absence of light (peroxidase‐like activity) and 1O2 on light irradiation (650 nm; 25 mW cm−2). This work highlights the potential of Cu−TMPP as a functional carrier of anionic guests such as drugs, for the combination therapy of cancer and other diseases. A cationic 3D metal‐organic framework of Cu−TMPP featuring an unprecedented [CuII8Cl6]10+ cluster secondary building units has been prepared and demonstrated to have peroxidase‐like activity and catalytic singlet oxygen generation ability.