Details

Autor(en) / Beteiligte

• Charles, Charles M.
• Noles, Marcelo
• Munezero, Aline
• Gallardo, Negli
• Bahamondes, Luis
• Bento, Silvana F.
• Pádua, Karla S.
• Nhauche, Marta
• Metelus, Sherly
• Cecatti, José G.
• Souza, Renato T.
• Pacagnella, Rodolfo C.

Titel

Risk factors related to the SARS‐CoV‐2 vaccine additional doses hesitancy among pregnant and non‐pregnant people of reproductive age and partners: A Brazilian cross‐sectional study

Ist Teil von

• International journal of gynecology and obstetrics, 2024-09, Vol.166 (3), p.1144-1160

Ort / Verlag

United States

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Objective The aim of this study was to assess the predictors of acceptance and hesitancy of additional doses of any SARS‐CoV‐2 (COVID‐19) vaccine among pregnant or recently pregnant and non‐pregnant people of reproductive age and partners in Brazil. Methods We conducted an online cross‐sectional study from June 2022 to April 2023 and invited women and partners between 18 and 49 years old to participate. We employed a snowball strategy to reach all potential eligible participants. Our primary outcome was the acceptance rate of the COVID‐19 booster vaccine. We estimated the frequency and percentage for the three groups and compared categorical variables using the Chi‐square test. Moreover, bivariate, backward stepwise regression, and subgroup analyses were performed to evaluate risk factors and predictors of COVID‐19 vaccine booster hesitancy. We reported the effect size as OR with a 95% CI. Results We included 1487 participants, and among them, 334 (22.5%) were pregnant or recently pregnant people, 905 (60.8%) were non‐pregnant people, and 247 (16.6%) were male partners. Pregnant and recently pregnant people showed greater hesitancy for the COVID‐19 vaccine booster than non‐pregnant people (28% vs 15%, P < 0.001) and male partners (28% vs 16%, P < 0.001). Non‐pregnant women accepted the COVID‐19 vaccine more often than pregnant or recently pregnant people (OR 1.75; 95% CI: 1.13–2.70). The associated factors to the reduced COVID‐19 vaccine booster acceptance were family income between US$ 566–945.00 (54%), evangelic religion (65%), concern about vaccine safety (80%) and perceived common vaccine importance (93%). Conclusion Pregnant people were more hesitant than non‐pregnant people to accept the COVID‐19 booster vaccine. Family income, religious beliefs, vaccine safety concerns, and perceived common vaccine importance were significant barriers to accepting COVID‐19 booster vaccines. The impact of these factors was more evident among pregnant or recently pregnant people, emphasizing the harmful effect of misinformation among this vulnerable population. Synopsis Pregnant people are more hesitant about COVID‐19 vaccine uptake compared to their counterparts, with social determinants and vaccine safety concerns being the key barriers.