Details

Autor(en) / Beteiligte

• Zhang, Zhen
• Li, Zheqi
• Shi, Yi
• Chen, Yongming

Titel

Molecular Bottlebrushes as Emerging Nanocarriers: Material Design and Biomedical Application

Ist Teil von

• Langmuir, 2024-04, Vol.40 (14), p.7286-7299

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• As a unique unimolecular nanoobject, molecular bottlebrushes (MBBs) have attracted great interest from researchers in nanocarriers attributed to their defined structure, size, and shape. MBBs with various architectures have been proposed and constructed with well-defined domains for loading “cargos”, including core, shell, and periphery functional groups. Compared with nanomaterials based on self-assembly, MBBs have lots of advantages, including facile synthesis, flexible compositions, favorable stability, and tunable size and shape, that make them a promising nanoplatform for various applications. This paper summarizes the recent progress during the past decade, with a focus on developments within the last five years in the synthesis of MBBs with different architectures, and uses them as nanocarriers in drug delivery, biological imaging, and other emerging applications.