Details

Autor(en) / Beteiligte

• Cortez, C.
• Tomaskovic-Crook, E.
• Johnston, A. P. R.
• Radt, B.
• Cody, S. H.
• Scott, A. M.
• Nice, E. C.
• Heath, J. K.
• Caruso, F.

Titel

Targeting and Uptake of Multilayered Particles to Colorectal Cancer Cells

Ist Teil von

• Advanced materials (Weinheim), 2006-08, Vol.18 (15), p.1998-2003

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2006

Quelle

Wiley Online Library All Journals

Beschreibungen/Notizen

• Core/shell particles and capsules formed by a layer‐by‐layer technique are biofunctionalized with a humanized A33 monoclonal antibody (huA33 mAb) that binds to the A33 antigen present on colorectal cancer cells (see figure). Targeting to a colorectal cancer cell line shows selective binding and internalization of particles.