Details

Autor(en) / Beteiligte

• Funnell, Mark P.
• Juett, Loris A.
• Reynolds, Kirsty M.
• Johnson, Drusus A.
• James, Ruth M.
• Mears, Stephen A.
• Cheuvront, Samuel N.
• Kenefick, Robert W.
• James, Lewis J.

Titel

Iterative assessment of a sports rehydration beverage containing a novel amino acid formula on water uptake kinetics

Ist Teil von

• European journal of nutrition, 2024-06, Vol.63 (4), p.1125-1137

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2024

Quelle

SpringerLink

Beschreibungen/Notizen

• Purpose Rapid gastric emptying and intestinal absorption of beverages is essential for rapid rehydration, and certain amino acids (AA) may augment fluid delivery. Three sugar-free beverages, containing differing AA concentrations (AA + PZ), were assessed for fluid absorption kinetics against commercial sugar-free (PZ, GZ) and carbohydrate-containing (GTQ) beverages. Methods Healthy individuals ( n  = 15–17 per study) completed three randomised trials. Three beverages (550–600 mL) were ingested in each study (Study 1: AA + PZ [17.51 g/L AA], PZ, GZ; Study 2: AA + PZ [6.96 g/L AA], PZ, GZ; Study 3: AA + PZ [3.48 g/L AA], PZ, GTQ), containing 3.000 g deuterium oxide (D 2 O). Blood samples were collected pre-, 2-min, 5-min, and every 5-min until 60-min post-ingestion to quantify maximal D 2 O enrichment (Cmax), time Cmax occurred (Tmax) and area under the curve (AUC). Results Study 1: AUC (AA + PZ: 15,184 ± 3532 δ‰ vs. VSMOW; PZ: 17,328 ± 3153 δ‰ vs. VSMOW; GZ: 17,749 ± 4204 δ‰ vs. VSMOW; P  ≤ 0.006) and Tmax ( P  ≤ 0.005) were lower for AA + PZ vs. PZ/GZ. Study 2: D 2 O enrichment characteristics were not different amongst beverages ( P  ≥ 0.338). Study 3: Cmax (AA + PZ: 440 ± 94 δ‰ vs. VSMOW; PZ: 429 ± 83 δ‰ vs. VSMOW; GTQ: 398 ± 81 δ‰ vs. VSMOW) was greater ( P  = 0.046) for AA + PZ than GTQ, with no other differences ( P  ≥ 0.106). Conclusion The addition of small amounts of AA (3.48 g/L) to a sugar-free beverage increased fluid delivery to the circulation compared to a carbohydrate-based beverage, but greater amounts (17.51 g/L) delayed delivery.